Chemitope Glycopeptide is at the forefront of carbohydrate and peptide chemistry, providing cutting-edge solutions for the design, production, and use of complex glycopeptides as therapeutic agents. We offer custom glycopeptide synthesis to meet the growing demand for structurally defined glycosylated peptides, as well as a series of glycan derivatives to help accelerate comprehension of the glycome.
Key Publications from the Chemitope Team
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope.
Nature Communications (2018).
Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.
Science Translational Medicine (2017).
Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors.
Proceedings of the National Academy of Sciences (2013).